Colace stool softener capsules are the #1 stool softener brand recommended by doctors and pharmacists. That’s in part because Colace has been a trusted name in safe, gentle, effective, comfortable relief from constipation for more than 55 years. In addition to occasional constipation and irregularity, Colace can also relieve constipation associated with a number of medical conditions. Colace is also stimulant-free, so you don’t have to worry about crazy additives keeping you up all night. The Online Drugstore carries Colace capsules in both 50- and 100-mg. strengths. Colace generally produces a bowel movement within 12 to 72 hours of taking the capsule. That’s because Colace contains docusate sodium, which allows water and fats to get into the stool. That results in softer fecal material, which makes defecation easier.